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br Acknowledgements br Introduction TB is also widely
2020-07-28
Acknowledgements Introduction TB is also widely prescribed as a stain to identify proteoglycans and glycosaminoglycans (GAGs) in agarose gel electrophoresis (Dietrich and Dietrich, 1976; Coulson-Thomas et al., 2015). In addition, as adjunct to a photodynamic antimicrobial chemotherapy assay, T
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DGK is a key enzyme in glucose uptake in skeletal
2020-07-28
DGKδ is a key enzyme in glucose uptake in skeletal muscle. Chibalin et al. demonstrated that a decrease in DGKδ expression increases the severity of type 2 diabetes [20]. Additionally, DGKδ expression was increased in people who exhibited enhanced insulin sensitivity after exercise training [56]. Fr
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Autophagy is initiated by conjugation of Atg and
2020-07-28
Autophagy is initiated by conjugation of Atg12, 5 and 8/microtubule-associated protein light chain 3 (LC3) to the nascent autophagosome membrane. During the formation of mammalian autophagosomes, two ubiquitination-like modifications are required, Atg12-conjugation and LC3-modification. The LC3 is a
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Radioligand selection may be the critical factor for detecti
2020-07-28
Radioligand selection may be the critical factor for detecting CRF1 receptor antagonists that bind to the ECD. Compounds with this site of action could be useful starting points for developing therapeutic agents with improved physical properties over J-site antagonists. However, it remains to be see
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br Materials and methods br Results br Discussion These find
2020-07-28
Materials and methods Results Discussion These findings suggest that, along with other factors that dysregulate fatty Chlorothiazide and lipid metabolism in HIV-infected people [29], several of the currently prescribed ritonavir-boosted HIV-PIs directly impair the ability of skeletal muscle
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In all ADEPT clinical studies using
2020-07-28
In all ADEPT clinical studies using antibody-enzyme conjugates, Compstatin to murine monoclonal antibodies and the bacterial enzyme (CPG2) were detectable in serum of patients within 10days after a single ADEPT cycle. Two or three ADEPT cycles were possible when patients were given cyclosporine A.
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Wlodkowski Wlodkowski and Kasworm present a history
2020-07-28
Wlodkowski, 2003, Wlodkowski and Kasworm, 2003 present a history of accelerated learning as a response to the preferences of older students and note the substantial offerings of such programs by US colleges and universities. Accelerated or intensive accounting programs can serve the dual purpose of
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Genomic DNA isolation Protist cells were digested
2020-07-27
Genomic DNA isolation. Protist cells were digested at 37°C for at least 1h with g/ml proteinase K in the presence of 10mM Tris–HCl, pH 8, 0.1M EDTA, 0.5% SDS, and g/ml DNAse-free RNAse. Samples were then subjected to extraction with phenol:chloroform followed by centrifugation. This procedure was re
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Mefenamic acid treated group In comparison with the control
2020-07-27
Mefenamic acid-treated group: In comparison with the control group, the liver of mefenamic acid-treated mice demonstrated hepatocytes hydropic degeneration, sinusoidal dilatation, Kupffer cells hyperplasia, pyknotic mitotic figures, apoptotic hepatocytes, bile duct hyperplasia, and occasional fatty
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Crm regulates these factors by interacting with their
2020-07-27
Crm1 regulates these factors by interacting with their NES and targeting them spatially and temporally to centrosomes. It is likely that Crm1 supplies a docking site for these factors at centrosomes and regulates their localization and function . But it is still unknown the mechanism for Crm1 to ta
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Forskolin is a labdane diterpene
2020-07-27
Forskolin is a labdane diterpene produced from the root of Coleus forskohlii (Bhat et al., 1977). Its extract has been recorded in Ayurveda medicine since ancient times and its medicinal value has been studied since early-1980s (Bristow et al., 1984; Kavitha et al., 2010). Early studies have suggest
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One contribution to knowledge of that research is
2020-07-27
One contribution to knowledge of that research is the POE Safety Pattern (PSP; [25]), shown on the right of Fig. 6, a process pattern for capturing high-level descriptions of system requirements and domain properties and assumptions through detailed problem models coupled with their traceable and ju
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Prior studies have shown that several variables such
2020-07-27
Prior studies have shown that several variables, such as gender, BMI, smoking status, physical exercise, stress levels, medications, and medical and/or psychological morbidities may influence the vagal control of HRV (Cohen et al., 1999). However, our study had a highly-controlled protocol for adjus
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Introduction The inflammation process involves sequential ac
2020-07-25
Introduction The inflammation process involves sequential activation of signaling molecules, pro-inflammatory mediators, such as prostaglandins, leukotrienes, and oxygen free radicals [1]. Two cyclooxygenases lpa receptor were responsible for activation of the production of prostaglandins (PG1s) a
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br Methods br Results br Discussion The findings of
2020-07-25
Methods Results Discussion The findings of this study indicate that an ET system including ET-1 and ET-2 as well as ET receptors are present in the retina and RPE/choroid, and are up-regulated by both hypertension and diabetes. Specifically, individual antagonism of the ETRA or ETRB deliver
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