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br Acknowledgement This work was supported
2022-09-15
Acknowledgement This work was supported by National Science Foundation (21475047, 21705051, 21874048), the Science and Technology Planning Project of Guangdong Province (2016B030303010), the Program for the Top Young Innovative Talents of Guangdong Province (2016TQ03N305) and the Foundation for H
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br Declaration of interest br Acknowledgments br
2022-09-15
Declaration of interest Acknowledgments This work was supported by grants from the Polish National Science Centre (PRELUDIUM grant no. 2013/11/N/NZ5/00270) and the European Commission FP7 Project Beta-JUDO (grant number 279 153), European Union EIT Health project DeTecT2D, Swedish Diabetes A
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Now we turn to the
2022-09-15
Now we turn to the other channel through which the risk-taking incentives provided by option compensation affect corporate debt maturity. Jensen and Meckling (1976) argue that the payoff structure of debt holders in a levered firm is concave, while that of equity holders is convex, thus, shareholder
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We also wonder what function
2022-09-15
We also wonder what function(s) both FPPS1 and FPPS2 genes had in leaf. As some research indicated that the alpha-farnesene was also detected in ripe leaf of crabapple (Malus sp.) (Wu et al., 2012), one or both of them may be related to the synthesis of alpha-farnesene in leaf. To our knowledge, the
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br Introduction Thrombosis is one of the
2022-09-15
Introduction Thrombosis is one of the leading causes of deaths in the cardiovascular diseases such as myocardial infarction (MI), unstable DMSO and acute coronary syndrome (ACS) in developed countries [1], [2]. It is estimated that venous thromboembolism (VTE) afflicts about 1 million (1–2 per 1
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In comparison to the standard HPLC
2022-09-15
In comparison to the standard HPLC assay to detect LPV above or below 1,000 ng mL-1, the accuracy of the PIs-IC strip was 97.8 %, the sensitivity was 100% and the specificity was 97.1 %. This suggests that the PIs-IC strip test has the potential accurately to semi-quantify PI concentrations in plasm
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CH 223191 synthesis br Discussion This study dedicated
2022-09-15
Discussion This study, dedicated to CH 223191 synthesis H3 and H4 receptors, was carried out on superfused tissues preincubated with 3H-choline or 3H-noradrenaline; electrical stimulation was used to elicit quasi-physiological exocytotic release of the respective transmitter. Since inhibition of
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br Introduction Coat colors are determined by both genetics
2022-09-13
Introduction Coat colors are determined by both genetics and environment, especially genetics. The phenotype of coat color of animals depends on two types of melanin, black to brown eumelanin and yellow to reddish brown pheomelanin produced in mammalian melanocyte (Ito et al., 2000; Ito and Wakam
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br Materials and methods br Results br Discussion Directly m
2022-09-13
Materials and methods Results Discussion Directly modulating specific target proteins and signaling pathways with small-molecule drugs or agonistic NHS-12-Biotin is widely used for cancer metastasis therapies [[39], [40], [41]]. ANXA7 acts as a metastasis suppressor in prostate cancer. How
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br Materials and methods br Results br Discussion Directly m
2022-09-13
Materials and methods Results Discussion Directly modulating specific target proteins and signaling pathways with small-molecule drugs or agonistic NHS-12-Biotin is widely used for cancer metastasis therapies [[39], [40], [41]]. ANXA7 acts as a metastasis suppressor in prostate cancer. How
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br Other Functions of HCA Receptors HCA
2022-09-09
Other Functions of HCA Receptors HCA receptors, in particular HCA1, are expressed in various primary tumor Sotalol 77, 78, 79. This is of interest, as most solid tumors show increased glucose uptake and lactate formation even under normoxic conditions, with lactate concentrations in the tumor mi
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Lean mass is representative of the
2022-09-09
Lean mass is representative of the muscle tissue mass equivalent of all the body parts containing water, excluding fat, bone minerals, and such substances which do not contribute to the NMR signal, such as hair, claws, etc. (ECHO-MRI (Houston, TX) user's manual). It was interesting that in the Bob-C
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Thyroid hormone triiodothyronine T and its precursor
2022-09-09
Thyroid hormone 3,5,3′-triiodothyronine (T3) and its precursor, thyroxine (T4), are iodinated compounds, which are known to regulate the expression of genes involved in various biological processes, such as development, growth and metabolic control. The iodothyronine deiodinase types I, II and III (
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Natural products have been always the
2022-09-09
Natural products have been always the most important and productive sources of lead compounds for the development of drugs [[15], [16], [17]]. A variety of potent α-glucosidase inhibitors have been identified from natural products, such as quercetin, resveratrol, isorhamnetin, calein C and curcumin
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Yeast two hybrid screening studies have provided the
2022-09-09
Yeast two-hybrid screening studies have provided the foundation for countless investigations of protein-protein interactions [[141], [142], [143]]. To identify additional hepatic proteins similar to GKRP that are implicated in GCK regulation, a group of researchers conducted a two-hybrid study using
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